FIGURE

Fig. 3

ID

ZDB-FIG-160816-7

Publication

Nord et al., 2016 - Pax7 is required for establishment of the xanthophore lineage in zebrafish embryos

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Fig. 3

The pax7a/pax7b double mutants have an increased number of melanoblasts. Whole-mount in situ hybridization on wt siblings and pax7a/pax7b double-mutant zebrafish embryo at 24 hpf showing the expression of (A) sox10 (n > 50 for siblings and n = 7 for pax7a/pax7b double mutants), (B) mitfa (n = 5 and 5), and (C) dct (n = 7 and 3). (D) Average number of mitfa⁺ and dct⁺ cells in the region anterior to the first somite on one side of wt siblings and pax7a/pax7b double-mutant embryos at 24 hpf; positive cells in the eye were excluded. Student’s t test was used to calculate significance; **p < 0.01. Error bars indicate SEM. Box indicates area of enlargement visualized in insets. Arrowheads indicate head region where changes in expression can be detected. Scale bar, 200 μm.

Expression Data

Genes:	dct mitfa sox10
Fish:	WT pax7a^umu3/umu3; pax7b^umu4/umu4
Anatomical Terms:	melanoblast melanocyte neural crest cell
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pax7a^umu3/umu3; pax7b^umu4/umu4
Observed In:	head melanoblast
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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