FIGURE

Fig. 6

ID

ZDB-FIG-160809-5

Publication

Stawicki et al., 2016 - Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish

Other Figures

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Fig. 6

Early developmental defects are not seen in the hair cells of zebrafish cilia mutants. (A) Phalloidin labeling of the stereocilia of 5 dpf zebrafish hair cells show no gross morphological defects in dync2h1 or cc2d2a mutants. Scale bar = 10 µm. (B) Earlier in development, at 3 dpf, dync2h1 mutants have grossly normal kinocilia. Scale bar = 10 µm. (C) Decreases in hair cell number in the absence of neomycin in dync2h1 mutants is not seen until 5 dpf. Data are shown as mean ± SD. n = 10 fish per group. **** P < 0.00001 by two-way ANOVA and Šídák multiple comparisons test. dpf, d post-fertilization; Mut, mutant; WT Sib, wild-type sibling.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cc2d2a^w38/w38 (AB) dync2h1^w46/w46 (AB)
Observed In:	neuromast hair cell stereocilium
Stage Range:	Long-pec to Days 7-13

Phenotype Detail

Acknowledgments

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