Fig. 6
Early developmental defects are not seen in the hair cells of zebrafish cilia mutants. (A) Phalloidin labeling of the stereocilia of 5 dpf zebrafish hair cells show no gross morphological defects in dync2h1 or cc2d2a mutants. Scale bar = 10 µm. (B) Earlier in development, at 3 dpf, dync2h1 mutants have grossly normal kinocilia. Scale bar = 10 µm. (C) Decreases in hair cell number in the absence of neomycin in dync2h1 mutants is not seen until 5 dpf. Data are shown as mean ± SD. n = 10 fish per group. **** P < 0.00001 by two-way ANOVA and ?ídák multiple comparisons test. dpf, d post-fertilization; Mut, mutant; WT Sib, wild-type sibling.