FIGURE

Fig. S11

ID

ZDB-FIG-160316-37

Publication

Xu et al., 2016 - Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration

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Fig. S11

Decreased Fhl1b activity inhibits liver and exocrine pancreas differentiation.

(A and B) Confocal images of Tg(ptf1a:GFP)^jh1 control embryos (A) and fhl1b morphants (B), stained for Prox1 (blue) and Islet (red). The expression domain of the Prox1 and Tg(ptf1a:GFP)^jh1 was reduced in fhl1b morphants (B) compared to that of control embryos (A). (C and D) Confocal images of Tg(fabp10a:RFP, ela3l:EGFP)^gz12 control embryos (C) and fhl1b MO-injected larvae (D) at 96 hpf. The expression domain of the Tg(fabp10a:RFP, ela3l:EGFP)^gz12 was reduced both in the liver and exocrine pancreas in fhl1b MO-injected larvae (D) compared to that of control larvae (C). A-D, confocal projection images, ventral views, anterior to the top. Scale bars, 20 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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