FIGURE

Fig. S1

ID

ZDB-FIG-151204-4

Publication

Pagán et al., 2015 - Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment

Other Figures

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Fig. S1

(Related to Figure 1). Adult csf1r mutant zebrafish have impaired macrophage development. (A) Flow cytometry plots and (B) absolute numbers of viable (DAPI-) splenic macrophages in 3-4 month-old wild-type (WT) and csf1r^-/- mpeg1:YFP fish. mpeg1:YFP- WT (non-transgenic, non-Tg) fish were used as negative controls. Each symbol represents individual larvae. (C) Flow cytometry plots and (D) absolute numbers of viable (DAPI-) liver macrophages in 3-4 month-old wild-type (WT) and csf1r^-/- mpeg1:YFP. Numbers above gated populations indicate percentages within parent population. Data are representative of two independent experiments (A) or were pooled from two experiments (B). Statistical significance determined by two-tailed unpaired Student’s t test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	csf1ra^{j4blue/j4blue}; w200Tg
Observed In:	liver macrophage spleen macrophage
Stage:	Adult

Phenotype Detail

Acknowledgments

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