FIGURE
Fig. 7
- ID
- ZDB-FIG-151124-8
- Publication
- Agarwala et al., 2015 - Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish
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Fig. 7
Loss of Lef1 suppresses the increased cell proliferation in amotl2a mutants. (A–D2) 30 hpf cldnb:gfp embryos with the indicated genetic background stained with a lef1 ISH probe and an anti-GFP antibody (B2, D′). (E) Boxplot showing the expansion of lef1 expression domain in MZamotl2a-/- embryos. (F–M) MIP of Z-stacks of pLLP in cldnb:gfp embryos with the indicated genotype, either uninjected (F–I) or injected with a Lef1Mo (J–M). (N) Corresponding boxplot comparing pLLP cell counts (Figure 7—source data 1, 2; Figure 7—figure supplement 1, Figure 7—source data 3). |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Term: | |
| Stage: | Prim-15 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Prim-15 |
Phenotype Detail
Acknowledgments
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