FIGURE

Fig. 6, S1

ID

ZDB-FIG-160413-10

Publication

Agarwala et al., 2015 - Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6, S1

Loss of Yap1 in MZamotl2a^-/-;MZyap1^-/- embryos supresses increased pLLP cell number resulting from loss of Amotl2a in MZamotl2a^-/- embryos.

The mutation of Yap1-binding domains in Amotl2a does not render it unstable. MIP of Z-stacks of pLLP in cldnb:gfp embryos with the indicated genotype (A–D). (E) Corresponding boxplot comparing pLLP cell counts. (F) Western blot showing the stability of wild-type Amotl2a, Amotl2aFL (lane2) and Amotl2a forms carrying both PPEA-LATA (lane3) and single PPEA and LATA (lanes 4 and 5), respectively. α-tubulin staining shows equal protein loading (Figure 6—source data 4).

Expression Data

Gene:	EGFP
Fish:	amotl2a^fu46/fu46; zf106Tg yap1^fu48/fu48; zf106Tg amotl2a^fu46/fu46; yap1^fu48/fu48; zf106Tg
Anatomical Term:	posterior lateral line primordium
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	amotl2a^fu46/fu46; zf106Tg yap1^fu48/fu48; zf106Tg amotl2a^fu46/fu46; yap1^fu48/fu48; zf106Tg
Observed In:	posterior lateral line primordium posterior lateral line primordium cell
Stage:	Prim-15

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife