FIGURE

Fig. 5

ID

ZDB-FIG-150506-9

Publication

Ablain et al., 2015 - A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish

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Fig. 5

Rescue of an Anemia Phenotype by Erythrocyte-Specific Targeting of p53

(A) Benzidine staining of rps29^-/- embryos injected with a pcmlc2:GFP, U6:gRNA, gata1:Cas9 vector targeting urod (ctrl) or p53 at 48 hpf.

(B) Quantification of the hemoglobin rescue in rps29^-/- embryos. urod (ctrl), n = 18 and p53, n = 20. Pooled results from two independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 32(6), Ablain, J., Durand, E.M., Yang, S., Zhou, Y., Zon, L.I., A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish, 756-64, Copyright (2015) with permission from Elsevier. Full text @ Dev. Cell