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Fig. 5
Rescue of an Anemia Phenotype by Erythrocyte-Specific Targeting of p53
(A) Benzidine staining of rps29-/- embryos injected with a pcmlc2:GFP, U6:gRNA, gata1:Cas9 vector targeting urod (ctrl) or p53 at 48 hpf.
(B) Quantification of the hemoglobin rescue in rps29-/- embryos. urod (ctrl), n = 18 and p53, n = 20. Pooled results from two independent experiments.
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Reprinted from Developmental Cell, 32(6), Ablain, J., Durand, E.M., Yang, S., Zhou, Y., Zon, L.I., A CRISPR/Cas9 Vector System for Tissue-Specific Gene Disruption in Zebrafish, 756-64, Copyright (2015) with permission from Elsevier. Full text @ Dev. Cell