FIGURE

Fig. 7

ID
ZDB-FIG-150428-23
Publication
Lepage et al., 2014 - Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly
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Fig. 7

Dynasore treatment does not cause major defects in EVL specification or apoptosis. ((A)(C)) Expression of keratin 4 (krt4), a marker of EVL differentiation, in untreated (A), DMSO control treated (B) and dynasore treated (C) embryos. Arrowheads in (C) indicate regions with reduced krt4 staining. ((D)(F)) Co-staining of untreated (D), DMSO treated (E) and dynasore treated (F) embryos with phalloidin and anti-cleaved Caspase 3, a marker of apoptotic cell death. Few Caspase 3-positive cells are observed in (F). Inset in (F) shows that these cells are not incorporated in the EVL.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 385(1), Lepage, S.E., Tada, M., and Bruce, A.E., Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly, 52-66, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.