FIGURE
Fig. S5
Fig. S5
Requirement of E-cadherin in pouch morphogenesis. (A-D) Forced expression of a dominant-negative N-terminally-truncated E-cadherin transgene in pouch endoderm (nkx2.3:Gal4VP16; UAS:&916;N-E-cadherin) resulted in reduced numbers of dysmorphic pouches (B), as well as fusions of CB cartilages (D). Scale bar: 40 Δm. (E) Quantification of pouch and CB defects. Data represent mean±s.e.m. *** shows P<0.001 relative to non-transgenic ‘wild-type’ siblings. Development |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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