FIGURE

Fig. 8

ID

ZDB-FIG-150309-13

Publication

Superina et al., 2014 - Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry

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Fig. 8

MZjek mutants have normal cilia length and normal fluid flow within Kupfferós vesicle (KV). (A,B) Confocal z-stack images through the KV of 6–8 SS wildtype (A) and MZjek (B) embryos that express membrane-localized mRFP (red) and Arl13b-GPF (green) demonstrate the presence of motile cilia. (C,D) Bead trajectories in wildtype and MZjek KVs injected with fluorescent beads at 8–10 SS. Representative bead trajectories in wildtype (C) and MZjek (D) indicated by arrows. (E) Mean and standard deviation of KV diameter, motile cilia length and range of motion of cilia in the KV of wildtype and MZjek embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ugdh^m310/m310
Observed In:	Kupffer's vesicle
Stage:	5-9 somites

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 387(2), Superina, S., Borovina, A., and Ciruna, B., Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry, 154-166, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.