FIGURE
Fig. 5
- ID
- ZDB-FIG-140923-30
- Publication
- Lin et al., 2014 - Hypoxia-Inducible Factor 2 Alpha Is Essential for Hepatic Outgrowth and Functions via the Regulation of leg1 Transcription in the Zebrafish Embryo
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Fig. 5
Knockdown of hif2-alpha damages liver cell proliferation. WT (Tg(lfabp:EGFP)) embryos (A) and hif2-alpha ATG-MO-injected embryos (B) were examined for liver cell proliferation using an anti-pH3 antibody at 4 dpf. Cell proliferation in hif2-alpha ATG-MO-injected embryos was reduced compared with WT embryos. (C) Quantification of pH3-positive cells in the liver (n = 11, p<0.05). (D) The EGFP-positive cells were counted by FACS. Quantification of pH3-positive cells in the trunk (E) and tail (F) (n = 4, p<0.05). |
Expression Data
| Gene: | |
|---|---|
| Antibody: | |
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Terms: | |
| Stage: | Day 4 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Day 4 |
Phenotype Detail
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Full text @ PLoS One