Fig. 3
Phox morphants have impaired neutrophil migration. (A–B) CAF2-dTomato C. albicans were microinjected into the hindbrain ventricle of Tg(mpx:GFP)i114 control (n = 7) or p47phox morphants (n = 8) and imaged for 4 hours. (A) Representative time-lapse images of control and p47phox morphants. Results are representative of at least three experiments with at least two fish per group per experiment. Scale bars represent 10 μm. (B) Total phagocytes and phagocytes with internalized fungi were counted at 4 hpi. Numbers from fish over three experiments were pooled and mean and standard error per fish are shown. *p<0.05 **p<0.01 as calculated by two-tailed Student′s T-test. |
Gene: | |
---|---|
Fish: | |
Anatomical Terms: | |
Stage: | Prim-25 |