FIGURE

Fig. 4

ID

ZDB-FIG-131105-19

Publication

Rosenfeld et al., 2013 - Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Hspb7 regulates ventricular cardiomyocyte size. (A) Representative phenotypes demonstrating the ventricular cell size observed in the indicated experimental conditions at 48 hpf in embryos derived from the myl7:actn3b; myl7:mKate-Caax reporter strain. The bars represent 10 μm. (B) Wildtype embryos (wt, n=3) or embryos injected with the standard control MO (control, n=4), hspb7 MO (hspb7, n=5), hspb12 MO (hspb12, n=3), or hspb7+12 MOs (hspb7+12, n=4) were evaluated with ImageJ to measure average cell area. At least seven cells were analyzed for each embryo to determine the average. The asterisk indicates p<0.05 by Student′s t-test in comparison to the standard control group.

Expression Data

Gene:	mKate2
Fish:	sd10Tg; sd11Tg sd10Tg; sd11Tg + MO1-hspb7 sd10Tg; sd11Tg + MO1-hspb12 sd10Tg; sd11Tg + MO1-hspb12 + MO1-hspb7
Knockdown Reagents:	MO1-hspb7 MO1-hspb12
Anatomical Term:	ventricular myocardium cardiac muscle cell
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sd10Tg; sd11Tg + MO1-hspb7 sd10Tg; sd11Tg + MO1-hspb12 sd10Tg; sd11Tg + MO1-hspb12 + MO1-hspb7
Knockdown Reagents:	MO1-hspb7 MO1-hspb12
Observed In:	ventricular myocardium cardiac muscle cell ventricular myocardium sarcomere organization
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 381(2), Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T., Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis, 389-400, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.