FIGURE

Fig. 2

ID

ZDB-FIG-130822-35

Publication

Sah et al., 2013 - Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

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Fig. 2

Trpm7 deletion in embryonic myocardium disrupts cardiac automaticity in vitro. (A) Ca²⁺ transients measured by high-speed line-scanning confocal microscopy in Trpm7^fl/fl EVM 4–5 d after transduction with Ad-CMV-Lacz (Top), Ad-CMV-Cre (Middle), and Ad-TnT-Cre (Bottom). (B) Mean Ca²⁺ transient frequency, (C) cycle length, C_L, (D) peak Ca²⁺ transients, F/F_o, and (E) Ca²⁺ transient length in Ad-CMV-Lacz, Ad-CMV-Cre, and Ad-TnT-Cre treated Trpm7^fl/fl EVMs. *P < 0.05, **P < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA