FIGURE

Fig. S4

ID

ZDB-FIG-130625-36

Publication

Schmid et al., 2013 - Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth

Other Figures

All Figure Page

Back to All Figure Page

Fig. S4

In situ hybridization of cardiac markers and microangiography in tardbp^-/-;tardbpl^-/- mutants. (A) cmlc2 primarily stains the ventricle whereas amhc. primarily stains the atrial myocardium. These markers do not reveal any obvious differences in wild-type and tardbp^-/-;tardbpl^-/- embryos. (Scale bars, 100 μm.) Ventral view, anterior to the left, 2 dpf. (B) Green fluorescently labeled beads were microinjected into the lumen of the blood vessels (microangiography) to visualize the lumen of the vasculature. (Top) A wild-type embryo; (Middle) a tardbp^-/-;tardbpl^-/- mutant. (Scale bar, 100 μm.) (Bottom) Higher magnifications of the area in the white box of the upper panels. (Scale bars, 50 μm.) Lateral view, anterior to the left, 2 dpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA