FIGURE

Fig. 3

ID

ZDB-FIG-130619-6

Publication

Ignatius et al., 2013 - Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development

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Fig. 3

Neural crest-derived posterior branchial arch progenitor specification is defective in hdac1^b382 mutants.

A, C, E, G, I, K wild-type embryos, B, D, F, H, J, L hdac1^b382 mutants. A, B Dorsal view of embryos at 25 hpf with dlx2 expression labeling the mandibular, hyoid and branchial arch precursor populations. C, D Lateral views of the head region at 25 hpf of crestin expression in the head region, black arrowheads indicate branchial arch populations. E, F, Lateral views of the head region at 25 hpf of hoxb3a expression in the hind-brain and branchial arch precursors. G, H, Lateral views of the head region at 96 hpf of col2a1 expression in mandibular, hyoid and branchial arches. I, J, Lateral views of the head region at 56 hpf of TUNEL-positive staining in the head and jaw regions. K, L, Side views of the head region at 32 hpf with tbx1 expression highlighting the endodermal pouches. M, mandibular; H, hyoid; BA, branchial arches.

Expression Data

Genes:	col2a1a crestin dlx2a hoxb3a tbx1
Fish:	WT hdac1^b382/b382
Anatomical Terms:	brain neural crest pharyngeal arch 1 pharyngeal arch 2 pharyngeal arch 3-7 pharyngeal pouch
Stage Range:	Prim-5 to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hdac1^b382/b382
Observed In:	pharyngeal arch 3-7 cell death
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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