FIGURE

Fig. 7

ID

ZDB-FIG-130619-10

Publication

Ignatius et al., 2013 - Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development

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Fig. 7

Effect of HDAC inhibition on sympathetic neuron differentiation is reversible.

A, B wild-type embryos treated with DMSO (A) and TSA (B) continuously from 28–52 hpf and then fixed at 52 hpf and stained for th expression, black arrowheads indicate sympathetic neurons. C–E wild-type embryos treated under three different conditions, C with DMSO between 28–72 hpf, D with TSA between 28–72 hpf, and E with TSA between 28–52 hpf after which the TSA is washed out and then the embryos are treated in DMSO between 52–72 hpf. All embryos were fixed at 72 hpf and then stained for th expression. Black arrowheads indicate th-xpressing sympathetic neurons, or their absence.

Expression Data

Gene:	th
Fish:	WT
Condition:	chemical treatment: pharmaceutical
Anatomical Terms:	brain sympathetic neuron
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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