FIGURE

Fig. 3

ID

ZDB-FIG-130308-2

Publication

Moriarty et al., 2012 - Loss of plakophilin 2 disrupts heart development in zebrafish

Other Figures

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Fig. 3

Blood pooling in morphant embryos. (A,B) Lateral view of O-dianisidine stained 72 hpf (A) control and (B) morpholino injected embryos. Blood was present in the anterior blood vessels, the heart, the common cardinal vein, the dorsal aorta, and posterior cardinal vein. In the morphant embryos, blood was pooled on the yolk prior to entering the heart. (C–F) The endothelial specific transgenic fli1:EGFP embryos injected with (E) control or (F) plakophilin 2 morpholino were analysed under light (C and D) and fluorescence microscopy (E and F) for vascular defects at 72 hpf. There was no alteration in vasculature in morphant embryos despite evident blood pooling (arrow).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO1-pkp2
Knockdown Reagent:	MO1-pkp2
Observed In:	blood circulation blood vasculature
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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