FIGURE

Fig. 4

ID

ZDB-FIG-130210-8

Publication

Yin et al., 2012 - Inhibition of the pim1 oncogene results in diminished visual function

Other Figures

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Fig. 4

Socs3a, Socs1 and Stat3 expression in 2–7 dpf retina.

First five panels are immunohistochemical analysis showing increasing expression of Socs3a, Socs1 and Stat3 throughout the retina from 2–7 dpf. Minimal staining is observed in secondary antibody alone, pre-immune serum or morphant controls. The last three panels are in-situ hybridisations of socs3a, socs1 and stat3 genes on 2 and 7 dpf. No significant staining was observed in sense probe controls. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer.

Expression Data

Genes:	socs1a socs3a stat3
Fish:	WT WT + MO3-socs1a WT + MO3-stat3 WT + MO3-stat3 + MO5-socs3a
Knockdown Reagents:	MO3-socs1a MO3-stat3 MO5-socs3a
Anatomical Terms:	eye lens retinal ganglion cell layer retinal inner nuclear layer retinal neural layer retinal outer nuclear layer
Stage Range:	Long-pec to Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-socs1a WT + MO3-stat3 WT + MO3-stat3 + MO5-socs3a
Knockdown Reagents:	MO3-socs1a MO3-stat3 MO5-socs3a
Observed In:	eye retinal neural layer Muller cell retinal photoreceptor layer retinal cone cell
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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