FIGURE

Fig. 7

ID

ZDB-FIG-120627-31

Publication

Porreca et al., 2012 - Zebrafish bcl2l is a survival factor in thyroid development

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Fig. 7

Thyroid development is severely impaired in bcl2l morphant embryos. Lateral views with anterior to the left of 48 hpf embryos. Experimental morpholino is indicated on the top and markers on the left of the figure, percentage (indicating the fraction of the described phenotype) at bottom left of each image. (A)–(E) pax2a staining in control MO (A), in bcl2l MO (B) and (C) injected embryos and in bcl2l MO and bcl2l mRNA co-injected embryos (D) and (E); (F)–(J) pax8 staining in control MO (F), in bcl2l MO (G) and (H) injected embryos and in bcl2l MO and bcl2l mRNA co-injected embryos (I) and (J); (K)–(O) nk2.1a staining in control MO (K), in bcl2l MO (L) and (M) injected embryos and in bcl2l MO and bcl2l mRNA co-injected embryos (N) and (O). Arrows point to thyroid primordium.

Expression Data

Genes:	nkx2.4b pax2a pax8
Fish:	WT WT + MO1-bcl2l1
Knockdown Reagent:	MO1-bcl2l1
Anatomical Term:	thyroid follicle
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-bcl2l1
Knockdown Reagent:	MO1-bcl2l1
Observed In:	thyroid follicle thyroid gland development
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 366(2), Porreca, I., De Felice, E., Fagman, H., Di Lauro, R., and Sordino, P., Zebrafish bcl2l is a survival factor in thyroid development, 142-152, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.