FIGURE
Fig. 5
- ID
- ZDB-FIG-120501-4
- Publication
- Matthews et al., 2005 - Zebrafish vps33b, an ortholog of the gene responsible for human arthrogryposis-renal dysfunction-cholestasis syndrome, regulates biliary development downstream of the onecut transcription factor hnf6
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Fig. 5
vps33b knockdown disrupts biliary ultrastructure. (A,B) Electron micrographs of biliary epithelial cells from 5 dpf wild-type (A) and vps33b morpholino injected (B) larvae. The wild-type biliary cell cytoplasm has a homogeneous appearance. (B) A small bile duct comprising two bile duct cells from a vps33b morpholino-injected larva. Cytoplasm appears heterogeneously with multiple vesicles (black arrows). hep, hepatoctye; bd, bile duct lumen; bdc, bile duct cell. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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