FIGURE

Fig. S3

ID

ZDB-FIG-120125-19

Publication

Powell et al., 2011 - Jamb and jamc are essential for vertebrate myocyte fusion

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Fig. S3

Combined knockdown of jamb and jamc does not result in a synthetic myogenesis phenotype. (A, B) Antisense morpholino oligonucleotide knockdown of expression of jamc in jamb^HU3319 embryos (A, right) or jamb in jamc^sa0037 embryos (B, right) does not result in any further disruption of myogenesis than that observed in jamb^HU3319 (A, left) or jamc^sa0037 (B, left) at 48 h. p. f., suggesting no synthetic effect of combined knockdown of both genes. Single confocal microscopy images of myotomes 12–13 in 48 h. p. f. embryos, stained for F-actin (cyan) and nuclei (red). Anterior left; scale bars represent 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	jam2a^{hu3319/hu3319} jam3b^sa37/sa37 jam2a^{hu3319/hu3319} + MO1-jam3b jam3b^sa37/sa37 + MO1-jam2a
Knockdown Reagents:	MO1-jam2a MO1-jam3b
Observed In:	fast muscle cell myoblast fusion
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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