FIGURE

Fig. 5

ID

ZDB-FIG-111128-83

Publication

Ben et al., 2011 - Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates

Other Figures

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Fig. 5

Fin and head abnormalities in MZta3 mutants. (A,B) MZta3 embryos at 2 dpf displaying hindbrain haemorrhage (arrow) and mild cyclopia (B). (C,D) Pectoral fins from Mta3 and MZta3 larvae stained with Alcian Blue, showing loss of asymmetry in mutant (D). Broken lines indicate the fin fold margin. (E-G) Cranial blood vessels marked by the fli::GFP transgene; background had been removed in lower monochrome panels for ease of observation. Note the mis-branched and merged vessels of the cerebellar central artery in the MZta3 embryos (F,G), beneath the haemorrhagic area. Posterior mesencephalic central artery is indicated by an asterisk. An, anterior; Po, posterior; Di, distal; Pr, proximal; L, left; R, right.

Expression Data

Gene:	EGFP
Fish:	si:ch211-185a18.2^i264/+; si:ch211-185a18.2ⁱ²⁶⁵; si:ch211-185a18.2^i262/+; y1Tg si:ch211-185a18.2ⁱ²⁶⁵; si:ch211-185a18.2^i262/+; y1Tg
Anatomical Term:	brain vasculature blood vessel endothelium
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	si:ch211-185a18.2^i264/+; si:ch211-185a18.2ⁱ²⁶⁵; si:ch211-185a18.2^i262/+ si:ch211-185a18.2^i264/+; si:ch211-185a18.2ⁱ²⁶⁵; si:ch211-185a18.2^i262/+; y1Tg
Observed In:	blood vessel morphogenesis brain vasculature cerebellar central artery determination of bilateral symmetry eye pectoral fin pectoral fin development
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

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