FIGURE

Fig. 6

ID

ZDB-FIG-110927-1

Publication

Klaassen et al., 2011 - Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels

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Fig. 6

Feedback measured in cones is reduced in the mutant zebrafish

(A) Light-induced feedback responses in wild-type (left) and mutant (right) zebrafish cones. Horizontal cells were hyperpolarized by full-field 1 s flashes of light while the recorded cone was saturated with a 20 µm spot of bright light. (B) IV relation of a cone I_Ca in control (green), 50 µM DNQX (red), and 30 µM KA (black) in wild-type (Bi, left) and mutant (Bii, left). Averaged DNQX- (red) and KA- (black) induced currents in wild-type (Bi, right) and mutants (Bii, right). The DNQX-induced current is significantly reduced in the mutant compared to the current in wild-type.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gja9a^{hu1795/hu1795}
Observed In:	regulation of synaptic transmission, glutamatergic sensory perception of light stimulus
Stage:	Adult

Phenotype Detail

Acknowledgments

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