FIGURE

Fig. 2

ID

ZDB-FIG-110816-32

Publication

Klaassen et al., 2011 - Synaptic transmission from horizontal cells to cones is impaired by loss of connexin hemichannels

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Fig. 2

Cx52.9 co-localizes with GluR2, Cx55.5, and Cx52.6 in zebrafish retinas.

The top panel shows co-localization of the Cx52.9 (green) antibody and GluR2-IR (red). GluR2 labels the tips of horizontal cell dendrites. This co-localization shows that Cx52.9 is present at the horizontal cell dendrites. Middle panel: Double labeling of Cx52.9 (green) and Cx55.5 (red). Red, green, and yellow plaques can be found, indicating that in some (parts) of the gap-junctions Cx55.5 co-localizes with Cx52.9. The bottom panel shows that there is co-localization of Cx52.6 (red) and Cx52.9 (green). Also for this combination, areas of co-expression of the two connexins can be found. This means that the three connexins co-localize in gap-junctions between horizontal cells. Scale bar = 10 μm (top panel). Scale bar = 5 μm (middle and bottom panel).

Expression Data

Genes:	gja9a gja9b gja10b
Antibodies:	Ab1-cx52.6 Ab1-cx52.9 Ab1-cx55.5 Ab1-gria2
Fish:	WT
Anatomical Terms:	horizontal cell dendrite horizontal cell gap junction retinal inner nuclear layer upper region retinal outer plexiform layer
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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