Fig. 2
Overview of vascular development in the head and brain (36–72 hpf). A-T, Maximum intensity confocal projections of immuno-fluorescently stained embryos carrying the endothelial reporter Tg(kdrl:GFP)1a116. Endothelium, green (GFP). Cell outlines, red (β-catenin). Ages (hpf) indicated on top. Abbreviations (see Table 1): vasculature, white (with apostrophe, right side). Neuroepithelium, yellow. Other structures, blue. Small white arrows, CtAs. White arrowheads in (G-I) PHBC-BA connections. Yellow asterisk, r5 GFP-positive neuroepithelial signal from the Tg(kdrl:GFP)1a116 reporter. A-J, Dorsal views. Age-matched images from the same embryo collected at dorsal (A-E) and ventral (F-J) levels. Anterior, left. Left side, bottom. K-O, Left lateral views. Anterior, left. Dorsal, up. P-T, Transverse cross-sections of the posterior hindbrain at approximately the r5-r6 level. Dorsal, up. Left side, left. Scale bar (A): 200 μm for A-O and 100 μm for (P-T). |
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Stage Range: | Prim-25 to Protruding-mouth |
Reprinted from Developmental Biology, 357(1), Ulrich, F., Ma, L.H., Baker, R.G., and Torres-Vazquez, J., Neurovascular development in the embryonic zebrafish hindbrain, 134-51, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.