FIGURE
Fig. 3
- ID
- ZDB-FIG-101129-9
- Publication
- Cheesman et al., 2011 - Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88
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Fig. 3
Up-regulation of Wnt signaling causes intestinal hyperplasia. (A) H&E-stained section of an 8-dpf WT (wt) intestinal bulb shows an orderly array of cells in the intestinal epithelium. (B) An 8-dpf axin1 mutant intestine is thicker (bracket) and has more disorganized epithelial cells (*). (C) At both 6 and 8 dpf, axin1 mutants have significantly more BrdU-labeled cells within the intestinal epithelium than wt (P < 0.0001). (D) At 8 dpf, axin1 mutant intestines have significantly more epithelial cells in the bulb and distal intestine vs. wt (P < 0.0001). (Scale bar: A and B, 25 μM.) 4 |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage Range: | Day 6 to Days 7-13 |
Phenotype Detail
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Full text @ Proc. Natl. Acad. Sci. USA