FIGURE
Fig. 3
- ID
- ZDB-FIG-101118-29
- Publication
- Song et al., 2010 - Neural and Synaptic Defects in slytherin, a Zebrafish Model for Human Congenital Disorders of Glycosylation
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Fig. 3
A. External srn phenotypes including bent tail and aberrant hindbrain (bracket) are rescued by GDP-fucose supplementation (3 embryos). Scale bar = 100 μm. B. GDP-fucose injection significantly reduced the percentage of mutants from 28.6±1.2% to 8.4±2.7% (576 embryos, 4 carrier pairs; Student′s test, p<0.0001). C. After GDP-fucose supplementation (2 embryos), protein fucosylation as assessed by AAL staining at 48 hpf is rescued throughout srn embryos, to levels similar to those in WT embryos. Scale bar = 100 μm. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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