FIGURE

Fig. 3

ID

ZDB-FIG-101021-3

Publication

Matsuda et al., 2010 - Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish

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Fig. 3

Notch signaling regulates expression of FGF signaling components. (A,B) atoh1a (A) and fgf10 (B) expression in leading and trailing proneuromasts (arrows) in wild-type and mib1^ta52b zebrafish embryos at 31 and 36 hpf. There is 1° expansion of atoh1a and fgf10 expression at 31 hpf and 2° expansion by 36 hpf in mib1^ta52b embryos. (C,D) fgfr1 (C) and pea3 (D) are expressed in a pattern complementary to atoh1a and fgf10 in the pLLp. Although subtle, fgfr1 and pea3 expression is reduced in the central cells in maturing proneuromasts (arrowheads). In mib1^ta52b embryos, fgfr1 and pea3 expression is reduced in large clusters of cells (1° reduction) at 31 hpf (arrowheads). fgfr1 and pea3 expression is reduced in a broader domain and is restricted to the edges of the pLLp (2° reduction) by 36 hpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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