FIGURE

Fig. 10

ID

ZDB-FIG-100211-41

Publication

Rikin et al., 2010 - The tbx/bHLH transcription factor mga regulates gata4 and organogenesis

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Fig. 10

Knockdown of p53 can rescue the mga morphant apoptosis in the head/brain. A-D: Shown are representative morphant embryos injected with (A) 7 ng or (C) 10 ng of mga MO1 morpholino followed by TUNEL staining at 48 hpf. Note that there is a significant and dose-dependent accumulation of apoptosis in the brain mainly in the midbrain (MB) and hindbrain (HB) regions. B, D: Apoptosis is either (B) fully or (D) significantly reduced when embryos are co-injected with 1 ng of p53 morpholino.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-mgaa WT + MO1-mgaa + MO1-tp53
Knockdown Reagents:	MO1-mgaa MO1-tp53
Observed In:	brain hindbrain midbrain
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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