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Fig. 10 Knockdown of p53 can rescue the mga morphant apoptosis in the head/brain. A-D: Shown are representative morphant embryos injected with (A) 7 ng or (C) 10 ng of mga MO1 morpholino followed by TUNEL staining at 48 hpf. Note that there is a significant and dose-dependent accumulation of apoptosis in the brain mainly in the midbrain (MB) and hindbrain (HB) regions. B, D: Apoptosis is either (B) fully or (D) significantly reduced when embryos are co-injected with 1 ng of p53 morpholino.
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