FIGURE

Fig. S1

ID

ZDB-FIG-091215-57

Publication

Lee et al., 2009 - Notch Signaling Functions as a Cell-Fate Switch between the Endothelial and Hematopoietic Lineages

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Fig. S1

DAPT Treatment Leads to an Increased Number of Endothelial Cells at the Fifth Somite Level
(A) Transverse sections of 18 hpf embryos, DMSO- or DAPT-treated, visualized for TOPRO (white), kdrl:GFP (green), and phalloidin (red). (B) Quantification of endothelial nuclei per focal plane in DMSO-treated (n=30) or DAPT-treated (n=35) embryos. Embryos treated with DAPT contained 5.74 (s=1.37) endothelial nuclei, while those treated with DMSO had 3.93 (s=1.57) nuclei per section (ANOVA, p<10^-5), indicating that the effect of Notch signaling on the number of endothelial cells is not limited to specific regions within the embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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