ZFIN Image: Lee et al., 2009, Fig. S1

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Figure Caption

Fig. S1 DAPT Treatment Leads to an Increased Number of Endothelial Cells at the Fifth Somite Level
(A) Transverse sections of 18 hpf embryos, DMSO- or DAPT-treated, visualized for TOPRO (white), kdrl:GFP (green), and phalloidin (red). (B) Quantification of endothelial nuclei per focal plane in DMSO-treated (n=30) or DAPT-treated (n=35) embryos. Embryos treated with DAPT contained 5.74 (s=1.37) endothelial nuclei, while those treated with DMSO had 3.93 (s=1.57) nuclei per section (ANOVA, p<10^-5), indicating that the effect of Notch signaling on the number of endothelial cells is not limited to specific regions within the embryos.

Acknowledgments

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