FIGURE

Fig. 2

ID

ZDB-FIG-091119-3

Publication

Malicki et al., 1996 - Mutations affecting development of the zebrafish ear

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Fig. 2

The ear phenotype of quadro (quo)^m271 mutants. In some mutant embryos the otocyst is split into two incomplete vesicles. A and B show the appearance of ears in the mutant at 36 hpf and 5 dpf respectively. Epithelial protrusions form but frequently do not develop into columns (arrowheads in B). At 14 hpf dlx-3 is expressed in the forming otic placode of wild-type embryos (arrowhead in C). In some mutant embryos, the dlx-3 expression domain is split into two smaller fields at this stage (arrowheads in D). In the wild-type ear the msx-C gene is expressed in three distinct patches at 60 hpf (arrows in E). The msx-C expression domains are frequently fused or absent in quo^m271 embryos at this stage (F). In all panels anterior is left and dorsal up.

Expression Data

Genes:	dlx3b msx3
Fish:	AB foxi1^m271/m271 (AB)
Anatomical Terms:	otic placode otic vesicle protrusion
Stage Range:	14-19 somites to Pec-fin

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	foxi1^m271/m271 (AB)
Observed In:	inner ear inner ear morphogenesis otic placode otic vesicle protrusion otolith pillar of the semicircular canal
Stage Range:	14-19 somites to Day 5

Phenotype Detail

Acknowledgments

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