Fig. 2

Fig. 2 The ear phenotype of quadro (quo)^m271 mutants. In some mutant embryos the otocyst is split into two incomplete vesicles. A and B show the appearance of ears in the mutant at 36 hpf and 5 dpf respectively. Epithelial protrusions form but frequently do not develop into columns (arrowheads in B). At 14 hpf dlx-3 is expressed in the forming otic placode of wild-type embryos (arrowhead in C). In some mutant embryos, the dlx-3 expression domain is split into two smaller fields at this stage (arrowheads in D). In the wild-type ear the msx-C gene is expressed in three distinct patches at 60 hpf (arrows in E). The msx-C expression domains are frequently fused or absent in quo^m271 embryos at this stage (F). In all panels anterior is left and dorsal up.