FIGURE

Fig. 5

ID

ZDB-FIG-090618-34

Publication

Tee et al., 2009 - Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Misexpression of mstn rescues axin1/apc1 embryos.

(A) Injection of 5 pg p21^CIP/WAF or mstn mRNA into 1 cell stage embryos, and phenotype assessment at 54 hpf. Slightly hypotrophic muscle fibers are observed in p21 as well as mstn-injected wild-type embryos confirming efficiency of misexpression. Muscle hypertrophy in mstn-injected axin1/apc1 embryos is partially restored to normal. (B) Quantification of the somite number of uninjected and p21^CIP/WAF or mstn mRNA (5 pg) injected embryos. (C) Misexpression of mstn partially restores the truncated somite phenotype, as well as cell survival in axin1/apc1. Scale bar, 0.5 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	apc^zf134/zf134; axin1^tm13/tm13
Observed In:	skeletal muscle cell somite whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One