ZFIN Image: Tee et al., 2009, Fig. 5

Image

Figure Caption

Fig. 5 Misexpression of mstn rescues axin1/apc1 embryos.

(A) Injection of 5 pg p21^CIP/WAF or mstn mRNA into 1 cell stage embryos, and phenotype assessment at 54 hpf. Slightly hypotrophic muscle fibers are observed in p21 as well as mstn-injected wild-type embryos confirming efficiency of misexpression. Muscle hypertrophy in mstn-injected axin1/apc1 embryos is partially restored to normal. (B) Quantification of the somite number of uninjected and p21^CIP/WAF or mstn mRNA (5 pg) injected embryos. (C) Misexpression of mstn partially restores the truncated somite phenotype, as well as cell survival in axin1/apc1. Scale bar, 0.5 mm.

Figure Data

Phenotype details

Acknowledgments

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