FIGURE

Fig. S5

ID

ZDB-FIG-090408-47

Publication

Málaga-Trillo et al., 2009 - Regulation of Embryonic Cell Adhesion by the Prion Protein

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Fig. S5

Accumulation of PrPs at Cell Contacts Correlates with Increased Levels of Tyrosine Phosphorylation in Drosophila S2 Cells

(A–E) Accumulation of mouse DsRed-monomer-PrP (m PrP) and zebrafish EGFP- and DsRed-monomer-PrP-2 (zf PrP-2) at S2 cell contacts colocalizes with anti-phosphoSrc (α-pSrc, [A]) and anti-phosphotyrosine immunostaining (α-pTyr, [B–E], arrowheads), indicating recruitment and activation of Src tyrosine kinases.

(F) A control mouse DsRed monomer-PrP lacking the PrP core does not cause this effect.

Scale bars indicate 5 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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