FIGURE

Fig. 12

ID

ZDB-FIG-080502-29

Publication

Farooq et al., 2008 - Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish

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Fig. 12

gdf11 negatively control exocrine pancreas growth in zebrafish. Pancreas formation was analyzed in gdf11 morphants by insulin (A–F) and elaB (G–H) expression. The endocrine pancreas formation (black arrow) was basically normal in gdf11 MO compared to 5 bp mismatch control morpholino injected embryos. A slight increase in insulin positive area was observed in about 10% of gdf11 MO at 5 dpf (F). elaB positive exocrine pancreas (white arrow) showed obvious increase in the majority of gdf11 MO at 5 dpf (H). Panels A–F are dorsal view while panels G–H are lateral view, anterior to the left. Scale bar is 100 μm.

Expression Data

Genes:	ela2l ins
Fish:	WT WT + MO1-gdf11
Knockdown Reagent:	MO1-gdf11
Anatomical Terms:	endocrine pancreas exocrine pancreas
Stage Range:	Long-pec to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-gdf11
Knockdown Reagent:	MO1-gdf11
Observed In:	exocrine pancreas
Stage:	Day 5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 317(1), Farooq, M., Sulochana, K.N., Pan, X., To, J., Sheng, D., Gong, Z., and Ge, R., Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish, 336-353, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.