FIGURE

Fig. 8

ID

ZDB-FIG-080418-28

Publication

Huang et al., 2003 - reg6 is required for branching morphogenesis during blood vessel regeneration in zebrafish caudal fins

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Fig. 8

Regenerating vessels in reg6 mutants show defects in branching. Time-lapse images from regenerating vessels of reg6;TG(fli1:EGFP)^y1 show defects in branching. (A) At 32 hpa (33°C), the regenerating vessels in reg6 mutants grow out with few branches and develop small bulbs at distal ends of individual arteries and veins (red and yellow arrows). These bulbs continue to grow through 35 hpa (B) and then form enlarged blisters a few hours later (C, red and yellow arrows) with fewer branches than wild type (also see Table 1). Note vessels denoted by red arrows fuse, while vessels denoted by yellow arrows remain distinct. Scale bar, 100 μm.

Expression Data

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Antibody Labeling

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Acknowledgments

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Reprinted from Developmental Biology, 264(1), Huang, C., Lawson, N.D., Weinstein, B.M., and Johnson, S.L., reg6 is required for branching morphogenesis during blood vessel regeneration in zebrafish caudal fins, 263-274, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.