Injection of either zebrafish or mouse Foxa2 mRNA restored the expression domain of ceruloplasmin in the liver of cdx1b morphants. Expression of ceruloplasmin in a 53 hpf wild type (A), respective morphants (B,C), an embryo co-injected with zebrafish foxa2 mRNA and cdx1b MO (D), an embryo co-injected with mouse Foxa2 mRNA and cdx1b MO (E), and respective embryos injected with either zebrafish foxa2 (F) or mouse Foxa2 (G) mRNA alone. (H) Comparison of the percentages of embryos showing reduced levels of the ceruloplasmin expression domain in respective embryos injected with either the cdx1b MO, zebrafish foxa2 mRNA and cdx1b MO, or mouse Foxa2 mRNA and cdx1b MO. Scale bar: 100 μm. wt, wild type.
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