FIGURE

Fig. 7

ID

ZDB-FIG-071116-6

Publication

Wingert et al., 2007 - The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros

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Fig. 7

Blocking RA Production in cdx Mutants Partially Rescues Pronephros Position and Distal Segment Formation. (A–C) Expression of cdh17, slc20a1a, and slc12a1 at 48 hpf in wild-type, cdx4^–/– mutants, and cdx-deficient embryos that were treated with DMSO (control) or DEAB from 90% epiboly to the 5 somite stage. Lines and numbers indicate expression domains and somite position, respectively. Arrows indicate podocyte and CS positions. Dorsal views are shown, with anterior to the left. Insets show enlarged dorsal views of podocyte (asterisk marks cystic glomeruli which stain weakly) and DL segment staining.

Expression Data

Genes:	cdh17 slc12a1 slc12a3 slc20a1a stc1l wt1b
Fish:	TU cdx4^{tv205c/tv205c} (TU) cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)
Condition:	chemical treatment: 4-(diethylamino)benzaldehyde
Knockdown Reagent:	MO2-cdx1a
Anatomical Terms:	corpuscles of Stannius podocyte posterior pronephric duct pronephric distal early tubule pronephric distal late tubule pronephric proximal convoluted tubule pronephric proximal straight tubule pronephric tubule
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU cdx4^{tv205c/tv205c} (TU) cdx4^{tv205c/tv205c} + MO2-cdx1a (TU)
Condition:	chemical treatment: 4-(diethylamino)benzaldehyde
Knockdown Reagent:	MO2-cdx1a
Observed In:	corpuscles of Stannius podocyte posterior pronephric duct pronephric distal early tubule pronephric distal late tubule pronephric glomerulus pronephric podocyte pronephric proximal convoluted tubule pronephric tubule
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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