FIGURE

Fig. 4

ID

ZDB-FIG-070925-59

Publication

Albertson et al., 2007 - Fgf8 haploinsufficiency results in distinct craniofacial defects in adult zebrafish

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Fig. 4

Fig. 4. Ace^ti282a/+ zebrafish exhibit aberrant craniofacial geometry. A relative warp analysis revealed two principal component axes that discriminate ace^ti282a/+ zebrafish from their wild-type siblings (A). The inset illustrates the position of fourteen landmarks used to describe the craniofacial skeleton in the lateral view. (B), Deformation grids as a function of the axes that differentiate ace^ti282a/+ and +/+ individuals. Ace^ti282a/+ animals exhibited an expanded frontal region of the skull (purple triangle), relative to the length of the posterior region of the cranium (green line). Ace^ti282a/+ zebrafish also exhibited coordinated changes in the configuration of the upper jaws (blue triangle), and in the relative height of the skull (yellow line).

Expression Data

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Antibody Labeling

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Acknowledgments

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Reprinted from Developmental Biology, 306(2), Albertson, R.C., and Yelick, P.C., Fgf8 haploinsufficiency results in distinct craniofacial defects in adult zebrafish, 505-515, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.