FIGURE

Fig. 1

ID

ZDB-FIG-070822-14

Publication

Giudicelli et al., 2007 - Setting the Tempo in Development: An Investigation of the Zebrafish Somite Clock Mechanism

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Fig. 1

Mapping of Temporal Oscillations into a Spatial Wave Pattern during Somite Segmentation, and a Model of the Oscillator Mechanism (A) The expression pattern of the oscillating gene deltaC in a zebrafish embryo at the ten-somite stage. (B) In each cell of the presomitic mesoderm, it is proposed that a her1 or her7 autoinhibition negative feedback loop generates oscillations. (C) Communication via the Delta-Notch pathway is proposed to keep oscillations in adjacent cells synchronized. The oscillations depend critically on the delays (T_m, T_p, T_md, and T_pd) in the feedback loops. (A–C) are slightly modified from [25].

Expression Data

Gene:	dlc
Fish:	WT
Anatomical Terms:	segmental plate somite tail bud
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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