FIGURE

Fig. 6

ID

ZDB-FIG-070219-15

Publication

Hernandez et al., 2007 - Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development

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Fig. 6

cyp26a1 protects against teratogenic effects of the RA precursor retinal. Wild-type (A) and cyp26a1^-/- (B) embryos injected with 20 pmol retinal at the one-cell stage. Wild-type embryos are only mildly affected by approximately triple the normal levels of retinal, whereas cyp26 mutants are Strongly posteriorized, with hoxd4 expression extending throughout the brain. Scale bar: 100 μm.

Expression Data

Genes:	egr2b hoxd4a pax2a
Fish:	cyp26a1^rw716/rw716
Condition:	chemical treatment: all-trans-retinal
Anatomical Term:	hindbrain
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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