Gene

hoxd4a

ID

ZDB-GENE-980526-214

Name

homeobox D4a

Symbol

hoxd4a Nomenclature History

Previous Names

hoxd4
etID309823.9 (1)
etID37000.9 (1)
fb36c05
wu:fb36c05 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and activating transcription factor binding activity. Involved in blood vessel morphogenesis and hemopoiesis. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neural keel; neural plate; presumptive structure; and vasculature. Orthologous to human HOXD4 (homeobox D4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

49 figures from 28 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu419 (23 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxd4a Human Ortholog

No data available

Associated With hoxd4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001827	Homeobox protein, antennapedia type, conserved site
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Domain	IPR020479	Homeodomain, metazoa
Family	IPR017995	Homeobox protein, antennapedia type
Family	IPR050609	Antp homeobox family, Deformed subfamily
Homologous_superfamily	IPR009057	Homedomain-like superfamily