FIGURE

Fig. 7

ID

ZDB-FIG-070126-7

Publication

Lee et al., 2006 - Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Blimp-1 function is necessary for shh expression whereas Hh signaling is required for maintenance, but not the initiation, of blimp-1 expression. (A-F) shh expression (arrows) in the ZPA of wild-type, ubo mutant and a blimp-1 morphant embryos at specific developmental stages. (G-I) blimp-1 expression (arrows) in embryos lacking Shh activity. (J-L) blimp-1 expression (arrows) in embryos lacking Smo activity. Panels A-F, G and J depict dorsal views; panels H, I, K and L show lateral views.

Expression Data

Genes:	prdm1a shha
Fish:	Df(Chr07)t4/t4 WT WT + MO2-prdm1a prdm1a^tp39 smo^b641
Knockdown Reagent:	MO2-prdm1a
Anatomical Terms:	mesenchyme pectoral fin pectoral fin pectoral fin bud zone of polarizing activity pectoral fin bud
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 300(2), Lee, B.C., and Roy, S., Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud, 623-634, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.