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Fig. 7 Blimp-1 function is necessary for shh expression whereas Hh signaling is required for maintenance, but not the initiation, of blimp-1 expression. (A-F) shh expression (arrows) in the ZPA of wild-type, ubo mutant and a blimp-1 morphant embryos at specific developmental stages. (G-I) blimp-1 expression (arrows) in embryos lacking Shh activity. (J-L) blimp-1 expression (arrows) in embryos lacking Smo activity. Panels A-F, G and J depict dorsal views; panels H, I, K and L show lateral views.
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Reprinted from Developmental Biology, 300(2), Lee, B.C., and Roy, S., Blimp-1 is an essential component of the genetic program controlling development of the pectoral limb bud, 623-634, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.